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Allele : Tnf<em2Boui> tumor necrosis factor; endonuclease-mediated mutation 2, Philippe Bouillet

Primary Identifier  MGI:6729284 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Tnf
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  The constitutive decay element (CDE) in the 3' UTR was targeted with gRNAs (targeting TGTCCTGGAGGACCCAGTGT and GGAGCTGAGCTGTCCCCACC) using CRISPR/Cas9 technology, resulting in a 71 bp deletion (AGGACCCAGTGTGGGAAGCTGTCTTCAGACAGACATGTTTTCTGTGAAAACGGAGCTGAGCTGTCCCCACC).
  • mutations:
  • Intragenic deletion
  • synonyms:
  • TNFdel5,
  • Tnf<del5>,
  • TNFdel5,
  • Tnf<del5>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele