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Allele : Tnf<em3Boui> tumor necrosis factor; endonuclease-mediated mutation 3, Philippe Bouillet
Primary Identifier  MGI:6729285 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Tnf
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  The new regulatory element (NRE) in the 3' UTR was targeted with gRNAs (targeting TTGTCTTAATAACGCTGATT and ATTTCTCTCAATGACCCGTA) using CRISPR/Cas9 technology, resulting in a 76 bp deletion (GCTGATTTGGTGACCAGGCTGTCGCTACATCACTGAACCTCTGCTCCCCACGGGAGCCGTGACTGTAATCGCCCTA).
  • mutations:
  • Intragenic deletion
  • synonyms:
  • TNFdel6,
  • TNFdel6,
  • Tnf<del6>,
  • Tnf<del6>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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