Primary Identifier | MGI:6728540 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change, Recombinase | Gene | Pdgfrb |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The targeting cassette consisting of a SA.lox.PDGFRb.lox-Flpo-attB-Neo-attP cassette replaced the exons 2-4 of the endogenous Pdgfrb gene. The PDGFRb is a mouse Pdgfrb gene cDNA. PhiC31 integrase removed the attB-Neo-attP cassette. Cre-mediated recombination is required to achieve expression of the flpo recombinase. |