| Primary Identifier | MGI:6721102 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Plxnb3 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The mutation is a deletion of exons 3â17 and part of exon 18 by replacing them with a sequence encoding for enhanced green fluorescent protein (EGFP) followed by a human growth hormone polyadenylation sequence and a neomycin resistance cassette. EGFP expression was not detected in the mutant animals. Endogenous Plexin-B3 mRNA and Plexin-B3 protein expression was undetectable via RT-PCR and Western blot analysis respectively, in brains of 4-week-old homozygous mice. |
