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Allele : Optn<tm1Hkawa> optineurin; targeted mutation 1, Hideshi Kawakami
Primary Identifier  MGI:6762162 Allele Type  Targeted
Attribute String  Null/knockout Gene  Optn
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The exon 8–10 of the Optn gene was replaced with a neomycin cassette (Neo) flanked by loxP sites via homologous recombination in ES cells. The absence of Optn protein in the homozygous mice were confirmed by immunoblotting of the lumbar spinal cords.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Optn KO,
  • Optn KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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