Primary Identifier | MGI:6723877 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(S100a4-flpo)3Lba |
Strain of Origin | mixed | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The transgenic construct containing a ~3 kbp genomic DNA fragment of the mouse S100a4 promoter that drives gene expression in fibroblasts driving the mouse codon-optimized Flp (Flpo) site-specific recombinase was injected into oocytes (FVB Ã B6 Ã DBA2 mixed background) to obtain founder mice. Six founder lines (#3, #4, #9, #11, #17, and #35) were generated. The highest and fibroblast specific expression of flpo mRNA was observed in line 3 and used for the study. |