| Primary Identifier | MGI:6764454 | Allele Type | Targeted |
| Attribute String | Null/knockout, Recombinase | Gene | Avpr1b |
| Transmission | Germline | Strain of Origin | (C57BL/6N x 129S6/SvEvTac)F1 |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | The Cre-nuclear localization sequence and FRT flanked pgk-neo cassette was inserted to replace the coding region from the initiating codon in exon 1 of the mouse Avpr1b gene by homologous recombination in the ES cells. The chimeras generated from correctly targetted ES cells were crossed to the FLPe deleter to remove the pgk-neo cassette. The absence of Avpr1b mRNA in brain of homozygous mice was confirmed. |
