| Primary Identifier | MGI:6758517 | Allele Type | Transgenic |
| Attribute String | Epitope tag, Humanized sequence, Inducible, Inserted expressed sequence | Gene | Tg(tetO-CCND1*K112E)#Rgp |
| Induced With | doxycycline/tetracycline | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A mutated form of the human cyclin D1 cDNA, preceded by sequence for an N-terminal 3xFLAG tag and followed by SV40 poly(A) signal sequences, was placed downstream of the tetracycline responsive element. The mutation is a G-to-A mutation that changes lysine codon 112 to a glutamic acid codon (p.K112E), eliminating or severely reducing the protein's phosphorylation (kinase) activity. |
