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Regulatory Region : Rr115 regulatory region 115

Primary Identifier	MGI:6836729	Organism	mouse, laboratory
Chromosome	5	Mgi Type	enhancer

description

PHENOTYPE: Deletion of this Shh brain enhancer in conjunction with heterozygous loss of Shh affects hypothalamus and craniofacial bone development and is perinatal lethal. [provided by MGI curators]

synonyms:
Rr115,
regulatory region 115,
SBE2

earliestPublication:
Sagai T, et al. (2019) SHH signaling mediated by a prechordal and brain enhancer controls forebrain organization. Proc Natl Acad Sci U S A 116(47):23636-23642

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Genome

Sequence Feature Displayer

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0 Genomic Clusters

2 Involved In Mutations

Trail: RegulatoryRegion

0 Transgenic Expressors

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Function

Mouse features --> Functions (GO terms)

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

Other

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