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Allele : Pms2<tm1.1Sks> PMS1 homolog2, mismatch repair system component; targeted mutation 1.1, Shyam Sharan
Primary Identifier  MGI:6764550 Allele Type  Targeted
Attribute String  Hypomorph Gene  Pms2
Transmission  Germline Strain of Origin  (C57BL/6J x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct replaced exon 11 with on containing the point mutation A to G that deletes the last 5 bp of exon 11 from the transcript by introducing a premature stop codon (I665*). Cre-mediated recombination removed floxed neomycin selection cassette into intron 11.
  • mutations:
  • Single point mutation
  • synonyms:
  • Pms2<ki>,
  • Pms2<ki>,
  • Pms2<c.1993AtoG>,
  • Pms2<c.1993AtoG>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele




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