Primary Identifier | MGI:6764576 | Allele Type | Targeted |
Attribute String | Conditional ready, Dominant negative, Inserted expressed sequence, Reporter, RMCE-ready | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting construct consisting of CMV enhancer sequence, a beta actin promoter, a floxed beta-geo stop cassette, loxN, Kozak-bovine tau/mTurquoise-WPRE-pA, lox2272, loxN, Kozak-bovine tau/tdTomato-IRES-dominant-negative rat Gnas mutant-WPRE-pA, lox2272 was inserted via homologous recombination. The allele allows stochastic Cre/lox recombination for functional mosaic analysis utilizing two distinct subpopulation after cre mediated recombination. |