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Allele : C9orf72<em3.1Aisa> C9orf72, member of C9orf72-SMCR8 complex; endonuclease-mediated mutation 3.1, Adrian Isaacs

Primary Identifier  MGI:6827372 Allele Type  Endonuclease-mediated
Gene  C9orf72 Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-targeting introduced 400 codon optimized GA repeats directly downstream of the ATG start codon. An FRT site flanked neomycin-PGK selection cassette was inserted at the 3’ end of the transgene. Flp-mediated recombination removed the neomycin-PGK cassette.
  • mutations:
  • Insertion
  • synonyms:
  • C9orf72<em1.1(GA400)Aisa>,
  • C9orf72<em1.1(GA400)Aisa>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele