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Allele : Gt(ROSA)26Sor<tm3(CAG-Irs2)Mschu> gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Markus Schubert
Primary Identifier  MGI:6861841 Allele Type  Targeted
Attribute String  Conditional ready, Epitope tag, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The CAG-a loxP site flanked neo-Westphal stop-FLAG-mouse Irs2 cassette followed by an FRT site-framed IRESeGFP expression cassette were inserted into ROSA26 locus via homologous recombination in the ES cells. In presence of cre recombinase, a loxP site flanked neo-Westphal stop sequence is removed to allow expression of FLG epitope-tagged mouse Irs2 driven by CAG promoter. Expression of flp recombinase removes FRT site-framed IRESeGFP.
  • mutations:
  • Insertion
  • synonyms:
  • IRS2<tg>,
  • IRS2<tg>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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