|  Help  |  About  |  Contact Us

Allele : Cttnbp2<em4Yph> cortactin binding protein 2; endonuclease-mediated mutation 4, Yi-Ping Hsueh

Primary Identifier  MGI:6761319 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Cttnbp2
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a G to T change resulting in an aspartic acid to tyrosine substitution at reside 570 (D570Y). In addition, an A to G change was introduced to modify the downstream MluCl site. D570Y is an autism spectrum disorder-linked mutation found in humans.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • D570Y,
  • D570Y
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele