Primary Identifier | MGI:6761769 | Allele Type | Targeted |
Attribute String | Conditional ready, Modified isoform(s), No functional change | Gene | Kif1b |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct introduced a loxP site and an FRT-flanked neomycin resistance cassette into intron 21 and an F3 flanked puromycin cassette and loxP site into intron 22. Flp-mediated recombination removed the selection cassettes and left exon 22 flanked by loxP sites. This allele impacts the beta isoform and not the alpha isoform. |