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Allele : Tigit<tm1.2Mrl> T cell immunoreceptor with Ig and ITIM domains; targeted mutation 1.2, Merck Research Laboratory
Primary Identifier  MGI:6833889 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tigit
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 and 3 was flanked by loxP sites (size of loxP-flanked region: 3.9 kb). Positive selection markers was flanked by FRT (Neomycin resistance - NeoR) and F3 (Puromycin resistance - PuroR) sites and were inserted into intron 1 and intron 3, respectively. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 2 and 3.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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