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Allele : Rbm20<em3Wguo> RNA binding motif protein 20; endonuclease-mediated mutation 3, Wei Guo

Primary Identifier  MGI:7266849 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Rbm20
Strain of Origin  C57BL/6NJ Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated an A to G change resulting in a serine to glycine substitution at amino acid 639 (p.S639G) in the RS domain. This is equivalent to the human S637G mutation seen in patients with severe dilated cardiomyopathy.
  • mutations:
  • Single point mutation
  • synonyms:
  • Rbm20<em1Hgra>,
  • Rbm20<S639G>,
  • Rbm20<em1Hgra>,
  • Rbm20<S639G>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele