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Allele : Prss3b<tm3.1Satom> serine protease 3B; targeted mutation 3.1, Miklos Sahin-Toth

Primary Identifier  MGI:6885796 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Prss3b
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  To mimic a mutation associated with hereditary pancreatitis in human (p.K23R), lysine codon 24 (AAA) in exon 2 was mutated to an arginine codon (AGA) (c.71A>G, p.K24R). A loxP site flanked neomycin resistance gene cassette was inserted into intron 1 and removed through subsequent cre-mediated recombination.
  • mutations:
  • Single point mutation
  • synonyms:
  • T7K24R,
  • T7K24R
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele