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Allele : Casp8<tm1.1Gne> caspase 8; targeted mutation 1.1, Genentech
Primary Identifier  MGI:7259812 Allele Type  Targeted
Attribute String  Not Specified Gene  Casp8
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  Aspartic acid codon 387 (GAT) in exon 9 was mutated to alanine (GCC) (p.D387A). The FRT site flanked neomycin selection gene cassette that was inserted into intron 9 was removed through subsequent flp-mediated recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Casp8<1xDA>,
  • Casp8<D387A>,
  • Casp8<D387A>,
  • Casp8<1xDA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele




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