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Publication : Calmodulin 4 is dispensable for epidermal barrier formation and wound healing in mice.

First Author  Lessard JC Year  2015
Journal  Exp Dermatol Volume  24
Issue  1 Pages  55-7
PubMed ID  25316000 Mgi Jnum  J:320850
Mgi Id  MGI:6880224 Doi  10.1111/exd.12568
Citation  Lessard JC, et al. (2015) Calmodulin 4 is dispensable for epidermal barrier formation and wound healing in mice. Exp Dermatol 24(1):55-7
abstractText  Calcium-mediated signals play important roles in epidermal barrier formation, skin homoeostasis and wound repair. Calmodulin 4 (Calm4) is a small, Ca2+ -binding protein with strong expression in suprabasal keratinocytes. In mice, Calm4 first appears in the skin at the time of barrier formation, and its expression increases in response to epidermal barrier challenges. In this study, we report the generation of Calm4 knockout mice and provide evidence that Calm4 is dispensable for epidermal barrier formation, maintenance and repair.
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