| Primary Identifier | MGI:7414393 | Allele Type | Endonuclease-mediated |
| Attribute String | Conditional ready, Null/knockout | Gene | Dnmt3a |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 4 was replaced by a reversed version of exon 4 that is flanked by lox71 and lox66 sites via CRISPR/Cas9 technology. Western blot analysis confirmed absence of protein expression (both isoform 1 and 2). The correct orientation of exon 4, and thus expression of isoform 1, is restored after cre-mediated recombination. |
