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Allele : Adar<em1Qwan> adenosine deaminase, RNA-specific; endonuclease-mediated mutation 1, Qingde Wang
Primary Identifier  MGI:7432329 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Adar
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-targeting modified the coding sequence to induce the amino acid substitution of glutamic acid with G > C nucleotide replacement (equivalent to c.3337 g > c in patients) which codes the Adar D963H mutation (the Adar D1113H mutation in humans).
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Adar D1113H,
  • Adar D1113H
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Trail: Allele

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Mouse alleles --> Mammalian phenotypes (MP terms)

 

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