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Allele : Tnfaip3<em1Stgr> tumor necrosis factor, alpha-induced protein 3; endonuclease-mediated mutation 1, Shane T Grey
Primary Identifier  MGI:7275310 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Tnfaip3
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  Using an sgRNA (targeting GGGATATCTGTAACACTCC) and an ssODN template (CACTGTCCTTCAGGGTCACCAGGGGTACAAAGTGCTGGCTGTCATAGCCTAGGACGATGGGATATCTGTAATACTCCTGAGCAGGCCAGTGAAGAGGCAGATAAATCCCACCCACTTTCAAAGGAGCAAAATTGGAACCAGATTCCAAAC) with CRISPR/Cas9 technology, cysteine codon 243 (TGT) was changed to tyrosine (TAT) (c.728G>A, p.C243Y).
  • mutations:
  • Single point mutation
  • synonyms:
  • Tnfaip3<C243Y>,
  • Tnfaip3<C243Y>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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