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Allele : Tnfaip3<em2Stgr> tumor necrosis factor, alpha-induced protein 3; endonuclease-mediated mutation 2, Shane T Grey
Primary Identifier  MGI:7275311 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Tnfaip3
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  Using an sgRNA (targeting TGACAATGATGGGTCTTCTGAGG) and an ssODN template (CTCCTCAGAGCTGAAACTCACCCAGGGAACCTAGAAACTCTCTGAGGCACCTCACCTGAAATGACAATGAGGGGTCTTCTGAGAATGTTGCTGAGGACAAATATGTGGATTTCTTCCAGGGAATTGTACTGAAGTCCACTTCGGGCTGCA) with CRISPR/Cas9 technology, isoleucine codon 207 (ATC) was changed to leucine (CTC) (c.619A>C, p.I207L).
  • mutations:
  • Single point mutation
  • synonyms:
  • Tnfaip3<I207L>,
  • Tnfaip3<I207L>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories





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