| Primary Identifier | MGI:7432545 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Adissp |
| Transmission | Germline | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The L1L2_gt1 cassette was inserted at position 130993292 of Chromosome 2 upstream of the critical exon 3 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon 3 at position 130994101. The critical exon 3 is thus flanked by loxP sites. Flp-mediated recombination removed the lacZ/neomycin sequence and generated a "conditional ready" (floxed) allele. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml |
