| Primary Identifier | MGI:7433054 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(CDX2-cre/ERT2)741Erf |
| Strain of Origin | C57BL/6J x SJL/J | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | The transgene was designed with a 9.5 kb promoter fragment from the 5' flanking sequences of human caudal type homeo box 2 (CDX2) gene, a creERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand binding domain), and a bovine growth hormone polyadenylation cassette. Compared to the CDX2P-CreER T2 transgenic line #752, transgenic line #741 shows increased tamoxifen-regulated Cre function in distal colon epithelium. |
