Primary Identifier | MGI:7262738 | Allele Type | Targeted |
Attribute String | Modified isoform(s) | Gene | Vdr |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The mutation is a deletion of the genomic sequences encoding the 12C-terminal amino acids and the introduction of two stop codons after codon 410. An Spe I restriction site was also engineered to allow detection of the mutant locus. A loxP flanked neomycin selection cassette was removed via Cre-mediated recombination. |