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Allele : Igh<tm12.1(IGHM)Cog> immunoglobulin heavy chain complex; targeted mutation 12.1, Michel Cogne

Primary Identifier  MGI:7711588 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Igh
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The human IGH mu constant sequence (with complete C1, -2, -3, -4, M1 and M2 exons and intervening introns) and a loxP site flanked neomycin resistance gene cassette were inserted into the Igh locus between the LS11 switch repeats downstream of enhancer hs4 (Rr91). The neo cassette was removed through subsequent Cre-mediated recombination.
  • mutations:
  • Insertion
  • synonyms:
  • LSRmuKI,
  • LSRmuKI
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele