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Allele : Gt(ROSA)26Sor<em8(CAG-Venus*,-Katushka2S)Murr> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 8, Stephen Murray
Primary Identifier  MGI:7279150 Allele Type  Endonuclease-mediated
Attribute String  Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6J-Gt(ROSA)26Sor<em7Mvw>/Mvw
Is Recombinase  false Is Wild Type  false
molecularNote  This knockin is a gene editing reporter with a Venus sequence interrupted by the insertion of a 47bp sgRNA sequence that replaces 9bp of sequence (GAGCGCACC, encoding Glu, Arg and Thr), followed by Katushka2S encoded in the +2 frame such that Venus expression indicates HDR and Katushka2S expression indicates NHEJ.
  • mutations:
  • Insertion
  • synonyms:
  • TLR-7,
  • TLR7,
  • TLR-7,
  • TLR7
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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