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Allele : Ripk3<tm1.1Vmd> receptor-interacting serine-threonine kinase 3; targeted mutation 1.1, Vishva M Dixit

Primary Identifier	MGI:7256694	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Ripk3
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A sequence fragment encompassing exons 1 through 3 was replaced with a loxP site flanked neomycin resistance gene cassette. Subsequent Cre-mediated recombination deleted the neo cassette.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Ripk3<->,
Ripk3<->

earliestPublication:
Newton K, et al. (2004) Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4. Mol Cell Biol 24(4):1464-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

25 Publication categories

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