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Allele : Slc7a14<em1Jin> solute carrier family 7 (cationic amino acid transporter, y+ system), member 14; endonuclease-mediated mutation 1, Zi-Bing Jin
Primary Identifier  MGI:7277696 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Slc7a14
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Using an sgRNA and an ssODN template with CRISPR/Cas9 technology, glycine codon 330 (GGC) in exon 6 was changed to arginine (AGG) (c.988_990delGGCinsAGG, p.G330R). This mimics the human p.G330R mutation associated with progressive sensorineural hearing loss and retinitis pigmentosa (RP).
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Slc7a14<c.AGG>,
  • Slc7a14<c.AGG>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele




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