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Allele : Idh1<em1Nbar> isocitrate dehydrogenase 1 (NADP+), soluble; endonuclease-mediated mutation 1, Nabeel Bardeesy
Primary Identifier  MGI:7263363 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Idh1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Using CRISPR-Cas9 technology in ES cells, a floxed STOP cassette (Lox-STOP-Lox) into the mouse genomic Idh1 locus upstream of a modified exon 3 engineered to contain a G → A transition in codon 132.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Idh1<R132H>,
  • Idh1<R132H>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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