| Primary Identifier | MGI:7258417 | Allele Type | Endonuclease-mediated |
| Gene | Casp8 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Using sgRNAs (targeting GTGTCGTCTATGGAACGGAT and GCCCATTAGAAGGTGCTTTA) and an ssODN template with CRISPR/Cas9 technology, cysteine codon 362 (TGC) was changed to serine (TCC) (p.C362S). This mutation allows the residue to be phosphorylated in the encoded peptide. |
