| Primary Identifier | MGI:7286320 | Allele Type | Endonuclease-mediated |
| Attribute String | Reporter | Gene | Gt(ROSA)26Sor |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting vector is designed to insert the ABE (Adenine Base Editor) reporter construct into the Gt(ROSA)26Sor locus containing a CAG promoter, mutated Venus*, bovine hGH, and polyA sequence. Venus* is a non-functional reporter that has codon 81 mutated into a stop codon. When an ABE together with a guide RNA that binds at the mutant site is introduced into cells, the stop is converted into a glutamine codon and the reporter will express GFP. |
