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Allele : Igk<tm3.1Cog> immunoglobulin kappa chain complex; targeted mutation 3.1, Michel Cogne
Primary Identifier  MGI:7377755 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Igk
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  The following sequences were inserted between Igkj segments and the Igk-Eik super-enhancer: murine Igh core switch region mu, human IGK-EIK super-enhancer, human IGK constant region, Igkv 4-63 promoter sequence and 1st exon with a STOP sequence, and murine Igh core switch region gamma3. The Rr152 (c3'RR) Igh enhancer cluster and a loxP site flanked neomycin resistance gene cassette were inserted downstream of the Igkc segment. Subsequent cre-mediated recombination removed the neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • c3'RR-KIKS,
  • c3'RR-KIKS
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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