| Primary Identifier | MGI:7378569 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Myoz3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AATGGCATTGGTGACAGGCG and ATTTGACCATTACCACCTAA, which resulted in a 619 bp deletion beginning at Chromosome 18 position 60,579,121 bp and ending after 60,579,739 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000355110 and ENSMUSE00000343269 (exons 4 and 5) and 429 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 72 and early truncation 5 amino acids later. |
