Primary Identifier | MGI:7290110 | Allele Type | Targeted |
Attribute String | Conditional ready, Endonuclease | Gene | Gt(ROSA)26Sor |
Inheritance Mode | Not Specified | Transmission | Germline |
Strain of Origin | C57BL/6JSmoc | Is Recombinase | false |
Is Wild Type | false |
molecularNote | These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Cas9 gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination. Cas9 is expressed when bred to mice that express Cre recombinase. |