| Primary Identifier | MGI:7290142 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | H2-Ab1 |
| Inheritance Mode | Not Specified | Strain of Origin | NOD.Cg-Prkdc<scid>/Smoc |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1 H2-AA H2-Eb1 H2-Eb2 H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the Nod-Scid genetic background and lacked cell surface expression of both class II-A and class II-E MHC proteins. |
