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Allele : Lepr<tm2Smoc> leptin receptor; targeted mutation 2, Shanghai Model Organisms Center
Primary Identifier  MGI:7290808 Allele Type  Targeted
Attribute String  Not Specified Gene  Lepr
Inheritance Mode  Not Specified Transmission  Germline
Strain of Origin  129S Is Recombinase  false
Is Wild Type  false
molecularNote  A point mutation was introduced to exon 19 (c.109052 G>T) via a recombineering strategy. Homozygous mutants are hyperphagic, low-activity, poorly cold-adapted, sterile and have enhanced fat conversion.
  • mutations:
  • Single point mutation
  • synonyms:
  • Lepr<tm1Smoc>,
  • Lepr-g.G109052T,
  • Lepr-g.G109052T,
  • Lepr<tm1Smoc>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele




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