Primary Identifier | MGI:7292989 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Trp53 |
Inheritance Mode | Not Specified | Transmission | Germline |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high,early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts. Click here for details |