Primary Identifier | MGI:7311562 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Thy1-CAST)12Rnix |
Strain of Origin | FVB/NJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgenic construct contains a mouse Thy1.1 (thymocyte differentiation antigen) promoter directing expression the human CAST (calpastatin) coding sequence. Founder line 12 expressed the highest amount of CAST protein (17 fold higher than controls). |