| Primary Identifier | MGI:7331507 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Scrn1 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTAAGATGATGGGGGAAAAT and CCAGCTTGAACAAAGCATGG, which resulted in a 471 bp deletion beginning at Chromosome 6 position 54,511,284 bp and ending after 54,511,754 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000192620 (exon 3) and 289 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 53 and early truncation 9 amino acids later. |
