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Allele : Tg(Slc6a3-tTA)2Kftnk transgene insertion 2, Kenji Tanaka
Primary Identifier  MGI:7316790 Allele Type  Transgenic
Attribute String  Transactivator Gene  Tg(Slc6a3-tTA)2Kftnk
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  BAC clone RP24-158J12 carrying mouse Slc6a3 (also carrying Lpcat1 (short isoform) and Clptm1l) was modified with a mammalianized tTA-Sv40 polyA signal introduced into the translation initiation site. The transgenic insertion site is unknown, but qPCR suggests that two copies of the BAC were integrated in the genome. A residual FRT and loxP site remain in the 3' end of the modified Slc6a3 segment. Founder line 2 carries higher transgene penetrance in dopamine neurons.
  • mutations:
  • Insertion
  • synonyms:
  • Slc6a3-tTA BAC,
  • Slc6a3-tTA BAC
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