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Allele : Gt(ROSA)26Sor<tm11(flpo)Amc> gene trap ROSA 26, Philippe Soriano; targeted mutation 11, Andrew P McMahon

Primary Identifier  MGI:7327519 Allele Type  Targeted
Attribute String  Conditional ready, Recombinase, RMCE-ready Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  true Is Wild Type  false
molecularNote  The following elements were inserted into the locus to create an RMCE (recombinase-mediated cassette exchange)-ready allele: a splice acceptor site, an ATG translation start site, an F3 site, a puromycin resistance gene cassette, a flpo recombinase gene cassette (with PGK promoter and poly(A) signal sequence), an FRT site and chicken beta-globin locus insulator sequence. When cells containing this allele are presented with a compatible RMCE vector, the sequence between the F3-FRT sites will be replaced with the sequence between the F3-FRT sites in the vector.
  • mutations:
  • Insertion
  • synonyms:
  • Rosa26 (FLPo),
  • Rosa26 (FLPo)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

3 Publication categories

Trail: Allele