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Allele : Mdm2<tm1.1Khv> transformed mouse 3T3 cell double minute 2; targeted mutation 1.1, Karen H Vousden
Primary Identifier  MGI:7328424 Allele Type  Targeted
Attribute String  Conditional ready Gene  Mdm2
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site, wild-type exons 11/12, FRT-flanked neomycin selection cassette, a second loxP site, and exons 11/12 containing the isoleucine to lysine substitution at amino acid 438 (p.I438K) in exon 12 replaced exons 11 and 12. The neomycin cassette was removed via flp-mediated recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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