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Allele : Jag1<em5Lutzy> jagged 1; endonuclease-mediated mutation 5, Cathy Lutz

Primary Identifier  MGI:7329948 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Jag1
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 genome editing was originally designed to introduce a S577R point mutation (AGC to AGA) and a silent mutation. DNA sequencing of the targeted region identified a founder instead harboring an 8 nucleotide deletion (indel mutation) after the sequence encoding amino acid 578.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Jag1 8 nt deletion,
  • Jag1 8 nt deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele