Primary Identifier | MGI:7329948 | Allele Type | Endonuclease-mediated |
Attribute String | Not Specified | Gene | Jag1 |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/cas9 genome editing was originally designed to introduce a S577R point mutation (AGC to AGA) and a silent mutation. DNA sequencing of the targeted region identified a founder instead harboring an 8 nucleotide deletion (indel mutation) after the sequence encoding amino acid 578. |