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Allele : Rr29<em4Axvi> regulatory region 29; endonuclease-mediated mutation 4, Axel Visel
Primary Identifier  MGI:7334960 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region, Null/knockout Gene  Rr29
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
molecularNote  Sequence for Shh enhancer ZRS or MFCS1 (mammals-fish conserved sequence 1), located in intron 5 of Lmbr1, was replaced with the same length (1324 bp) orthologous Burmese python sequence (12,740-14,063 (Python_molurus_bivi ttatus-5.0.2-2355.6; Genebank ID AEQU02119490.1)) using an sgRNA (targeting AGTACCATGCGTGTGTGTGA) and a plasmid DNA template with CRISPR/Cas9 technology.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Shh-pZRS<em4Axvi>,
  • Shh-pZRS<em4Axvi>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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