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Allele : Gdf6<em1Jiawa> growth differentiation factor 6; endonuclease-mediated mutation 1, Jian Wang

Primary Identifier  MGI:7482682 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Gdf6
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  Tyrosine codon 443 (TAT) was changed to asparagine (AAT) (c.1327T>A p.Y443N) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This mutation is the equivalent of the human p.Tyr444Asn associated with multiple synostoses syndromes (SYNS).
  • mutations:
  • Single point mutation
  • synonyms:
  • Gdf6 p.Tyr443Asn,
  • Gdf6<Y443N>,
  • Gdf6 p.Tyr443Asn,
  • Gdf6<Y443N>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele