| Primary Identifier | MGI:7482709 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Runx3 |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted in exon one 5' of the N-terminal region and a loxP and FRT flanked neo cassette was inserted 3' of exon 1. Cre mediated recombination removed the neo cassette and the N-terminal region of exon 1. Western blot analysis confirmed the absence of expression of the RUNX3(P1) protein that has a distinct set of 19 N-terminal amino acids compared to the RUNX3(P2) protein. |
