| Primary Identifier | MGI:7341598 | Allele Type | Endonuclease-mediated |
| Attribute String | Modified regulatory region | Gene | Rr278 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This CHD4/GATA4/NKX2-5/TBX5-binding site-containing 414 bp cis-regulatory element (CRE) in Myh11 intron 3, suppressing Myh11 expression, was targeted with sgRNAs using CRISPR/Cas9 technology, resulting in the deletion of the GATA-binding region all four transcription factors bind to. |
